Varaico: Literature-Extracted Genetic Variants

Gene:RNF43
Variant:p.R389H
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RNF43

NM_017763.6:p.R389H

Associated Papers

A phospho-switch controls RNF43-mediated degradation of Wnt receptors to suppress tumorigenesis.

Tsukiyama T et al.

Nature Communications, 2020

Commonly observed RNF43 mutations retain functionality in attenuating Wnt/β-catenin signaling and unlikely confer Wnt-dependency onto colorectal cancers.

Li S et al.

Oncogene, 2020

Landscape of somatic mutations in different subtypes of advanced breast cancer with circulating tumor DNA analysis.

Yi Z et al.

Scientific Reports, 2017

28729728 (PubMed )
Supplement: 41598_2017_6327_MOESM1_ESM.pdf

RNF43 and ZNRF3 are commonly altered in serrated pathway colorectal tumorigenesis.

Bond CE et al.

Oncotarget, 2016

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."