Varaico: Literature-Extracted Genetic Variants

Gene:RNF43
Variant:p.R127P
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RNF43

NM_017763.6:p.R127P

Associated Papers

RNF43 and ZNRF3: Versatile regulators at the membrane and their role in cancer.

Li S et al.

Biochimica Et Biophysica Acta. Reviews on Cancer, 2024

New Target(s) for RNF43 Regulation: Implications for Therapeutic Strategies.

Nag JK et al.

International Journal of Molecular Sciences, 2024

New insights in ubiquitin-dependent Wnt receptor regulation in tumorigenesis.

Tsukiyama T

In Vitro Cellular & Developmental Biology. Animal, 2024

The Functional Landscape of Patient-Derived RNF43 Mutations Predicts Sensitivity to Wnt Inhibition.

Yu J et al.

Cancer Research, 2020

A phospho-switch controls RNF43-mediated degradation of Wnt receptors to suppress tumorigenesis.

Tsukiyama T et al.

Nature Communications, 2020

Protease associated domain of RNF43 is not necessary for the suppression of Wnt/β-catenin signaling in human cells.

Radaszkiewicz T et al.

Cell Communication and Signaling : Ccs, 2020

Whole-exome sequencing of neoplastic cysts of the pancreas reveals recurrent mutations in components of ubiquitin-dependent pathways.

Wu J et al.

Proceedings of the National Academy of Sciences of the United States of America, 2011

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."