Varaico: Literature-Extracted Genetic Variants

Gene:RNF5
Variant:p.C42S
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RNF5

NM_006913.4:p.C42S

Associated Papers

E3 ubiquitin ligase RNF5 attenuates pathological cardiac hypertrophy through STING.

Yang LL et al.

Cell Death & Disease, 2022

Ring finger protein 5 activates sterol regulatory element-binding protein 2 (SREBP2) to promote cholesterol biosynthesis via inducing polyubiquitination of SREBP chaperone SCAP.

Kuan YC et al.

The Journal of Biological Chemistry, 2020

The deubiquitinase CYLD is a specific checkpoint of the STING antiviral signaling pathway.

Zhang L et al.

Plos Pathogens, 2018

Dissection of the Role of VIMP in Endoplasmic Reticulum-Associated Degradation of CFTRΔF508.

Hou X et al.

Scientific Reports, 2018

Inhibition of post-translational N-glycosylation by HRD1 that controls the fate of ABCG5/8 transporter.

Suzuki S et al.

Scientific Reports, 2014

STT3B-dependent posttranslational N-glycosylation as a surveillance system for secretory protein.

Sato T et al.

Molecular Cell, 2012

Sequential quality-control checkpoints triage misfolded cystic fibrosis transmembrane conductance regulator.

Younger JM et al.

Cell, 2006

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."