Associated Papers
p53-dependent chromatin relaxation is required for DNA double-strand break repair.
Chen H et al.
Acta Biochimica Et Biophysica Sinica, 2025
The p97-Ataxin 3 complex regulates homeostasis of the DNA damage response E3 ubiquitin ligase RNF8.
Singh AN et al.
The Embo Journal, 2019
RNF8 mediates NONO degradation following UV-induced DNA damage to properly terminate ATR-CHK1 checkpoint signaling.
Deshar R et al.
Nucleic Acids Research, 2019
Ataxin-3 consolidates the MDC1-dependent DNA double-strand break response by counteracting the SUMO-targeted ubiquitin ligase RNF4.
Pfeiffer A et al.
The Embo Journal, 2017
Cell cycle-regulated ubiquitination of tankyrase 1 by RNF8 and ABRO1/BRCC36 controls the timing of sister telomere resolution.
Tripathi E et al.
The Embo Journal, 2017
A Generic Platform for Cellular Screening Against Ubiquitin Ligases.
Maculins T et al.
Scientific Reports, 2016
Histone H1 couples initiation and amplification of ubiquitin signalling after DNA damage.
Thorslund T et al.
Nature, 2015
ATDC (Ataxia Telangiectasia Group D Complementing) Promotes Radioresistance through an Interaction with the RNF8 Ubiquitin Ligase.
Yang H et al.
The Journal of Biological Chemistry, 2015
Fine-tuning of DNA damage-dependent ubiquitination by OTUB2 supports the DNA repair pathway choice.
Kato K et al.
Molecular Cell, 2014
JMJD1C demethylates MDC1 to regulate the RNF8 and BRCA1-mediated chromatin response to DNA breaks.
Watanabe S et al.
Nature Structural & Molecular Biology, 2013
Ubiquitin-dependent recruitment of the Bloom syndrome helicase upon replication stress is required to suppress homologous recombination.
Tikoo S et al.
The Embo Journal, 2013
Dma/RNF8 proteins are evolutionarily conserved E3 ubiquitin ligases that target septins.
Chahwan R et al.
Cell Cycle (georgetown, Tex.), 2013
The RING finger protein RNF8 ubiquitinates Nbs1 to promote DNA double-strand break repair by homologous recombination.
Lu CS et al.
The Journal of Biological Chemistry, 2012
RNF8 regulates assembly of RAD51 at DNA double-strand breaks in the absence of BRCA1 and 53BP1.
Nakada S et al.
Cancer Research, 2012
Tandem protein interaction modules organize the ubiquitin-dependent response to DNA double-strand breaks.
Panier S et al.
Molecular Cell, 2012
A new non-catalytic role for ubiquitin ligase RNF8 in unfolding higher-order chromatin structure.
Luijsterburg MS et al.
The Embo Journal, 2012
The ubiquitin-selective segregase VCP/p97 orchestrates the response to DNA double-strand breaks.
Meerang M et al.
Nature Cell Biology, 2011
Nucleotide excision repair-induced H2A ubiquitination is dependent on MDC1 and RNF8 and reveals a universal DNA damage response.
Marteijn JA et al.
The Journal of Cell Biology, 2009
Regulation of mitotic exit by the RNF8 ubiquitin ligase.
Plans V et al.
Oncogene, 2008
Orchestration of the DNA-damage response by the RNF8 ubiquitin ligase.
Kolas NK et al.
Science (new York, N.y.), 2007
RNF8 ubiquitylates histones at DNA double-strand breaks and promotes assembly of repair proteins.
Mailand N et al.
Cell, 2007
The RING finger protein, RNF8, interacts with retinoid X receptor alpha and enhances its transcription-stimulating activity.
Takano Y et al.
The Journal of Biological Chemistry, 2004