Associated Papers
RNF8 ubiquitylation of XRN2 facilitates R-loop resolution and restrains genomic instability in BRCA1 mutant cells.
Krishnan R et al.
Nucleic Acids Research, 2023
RNF8-ubiquitinated KMT5A is required for RNF168-induced H2A ubiquitination in response to DNA damage.
Lu X et al.
Faseb Journal : Official Publication of the Federation of American Societies for Experimental Biology, 2021
RNF8 has both KU-dependent and independent roles in chromosomal break repair.
Tsai LJ et al.
Nucleic Acids Research, 2020
Ubiquitin ligase RNF8 suppresses Notch signaling to regulate mammary development and tumorigenesis.
Li L et al.
The Journal of Clinical Investigation, 2018
The E3 ubiquitin ligase Rnf8 stabilizes Tpp1 to promote telomere end protection.
Rai R et al.
Nature Structural & Molecular Biology, 2011
DNA-damage response and repair activities at uncapped telomeres depend on RNF8.
Peuscher MH et al.
Nature Cell Biology, 2011
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