Varaico: Literature-Extracted Genetic Variants

Gene:RNPEP
Variant:p.E106D
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RNPEP

NM_020216.4:p.E106D

Associated Papers

Regulation of Orai1/STIM1 mediated ICRAC by intracellular pH.

Gavriliouk D et al.

Scientific Reports, 2017

2-Aminoethoxydiphenyl Borate Potentiates CRAC Current by Directly Dilating the Pore of Open Orai1.

Xu X et al.

Scientific Reports, 2016

Structural and stoichiometric determinants of Ca2+ release-activated Ca2+ (CRAC) channel Ca2+-dependent inactivation.

Scrimgeour NR et al.

Biochimica Et Biophysica Acta, 2014

Glu¹⁰⁶ in the Orai1 pore contributes to fast Ca²⁺-dependent inactivation and pH dependence of Ca²⁺ release-activated Ca²⁺ (CRAC) current.

Scrimgeour NR et al.

The Biochemical Journal, 2012

21967483 (PubMed )
Supplement: supplement_1.pdf

Store-dependent and -independent modes regulating Ca2+ release-activated Ca2+ channel activity of human Orai1 and Orai3.

Zhang SL et al.

The Journal of Biological Chemistry, 2008

Orai1 mutations alter ion permeation and Ca2+-dependent fast inactivation of CRAC channels: evidence for coupling of permeation and gating.

Yamashita M et al.

The Journal of General Physiology, 2007

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."