Varaico: Literature-Extracted Genetic Variants

Gene:ROS1
Variant:p.R240K
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ROS1

NM_001378902.1:p.R240K

Associated Papers

Prevalence of Genomic Alterations in EGFR, KRAS, NRAS, and BRAF Among Early-Stage Nonsquamous Non-Small Cell Lung Cancer in Brazil.

Marques FK et al.

Jco Global Oncology, 2026

A prospective, multicenter, comprehensive genomic profile signature study in patients with EGFR-mutant advanced non-small cell lung cancer at the first-line treatment failure of osimertinib.

Shi Y et al.

Signal Transduction and Targeted Therapy, 2025

41326340 (PubMed )
Supplement: 41392_2025_2481_MOESM1_ESM.docx

De Novo EGFR -ALK and EGFR -ROS1 Co-Mutations in NSCLC: Clinical Characteristics, Molecular Profiling, and Treatment Outcomes From a Retrospective Analysis.

Shen L et al.

Cancer Medicine, 2025

40879219 (PubMed )
Supplement: CAM4-14-e71084-s003.xlsx › S3

Inflammatory Giant Cell Carcinoma of the Lung: Clinicopathologic, Immunohistochemical, and Next-generation Sequencing Study of 14 Cases.

Suster DI et al.

The American Journal of Surgical Pathology, 2024

Genomic features of lung cancer patients in Indonesia's national cancer center.

Hanafi AR et al.

Bmc Pulmonary Medicine, 2024

Case report: olaparib use in metastatic lung adenocarcinoma with BRCA2 pathogenic variant.

Soon Jian Hao J et al.

Cold Spring Harbor Molecular Case Studies, 2022

36577523 (PubMed )
Supplement: supp_mcs.a006223_Supplemental_Material.pdf

Comprehensive analyses of genomic features and mutational signatures in adenosquamous carcinoma of the lung.

Wang H et al.

Frontiers in Oncology, 2022

A Nationwide Study on the Impact of Routine Testing for EGFR Mutations in Advanced NSCLC Reveals Distinct Survival Patterns Based on EGFR Mutation Subclasses.

Koopman B et al.

Cancers, 2021

EGFR Exon 18 Mutations in Advanced Non-Small Cell Lung Cancer: A Real-World Study on Diverse Treatment Patterns and Clinical Outcomes.

Xu H et al.

Frontiers in Oncology, 2021

Identification of the Unique Clinical and Genetic Features of Chinese Lung Cancer Patients With EGFR Germline Mutations in a Large-Scale Retrospective Study.

Lin X et al.

Frontiers in Oncology, 2021

A comprehensive study on the oncogenic mutation and molecular pathology in Chinese lung adenocarcinoma patients.

Zhang X et al.

World Journal of Surgical Oncology, 2020

Spectrum of driver mutations and clinical impact of circulating tumor DNA analysis in non-small cell lung cancer: Analysis of over 8000 cases.

Mack PC et al.

Cancer, 2020

Genome analysis of peeling archival cytology samples detects driver mutations in lung cancer.

Kunimasa K et al.

Cancer Medicine, 2020

Identifying a wide range of actionable variants using capture-based ultra-deep targeted sequencing in treatment-naive patients with primary lung adenocarcinoma.

Chen L et al.

International Journal of Clinical and Experimental Pathology, 2020

Genomic Signature of Driver Genes Identified by Target Next-Generation Sequencing in Chinese Non-Small Cell Lung Cancer.

Wen S et al.

The Oncologist, 2019

Epidermal Growth Factor Receptor Mutation Frequency in Squamous Cell Carcinoma and Its Diagnostic Performance in Cytological Samples: A Molecular and Immunohistochemical Study.

Kumari N et al.

World Journal of Oncology, 2019

Heterogeneous Responses to Epidermal Growth Factor Receptor (EGFR) Tyrosine Kinase Inhibitors (TKIs) in Patients with Uncommon EGFR Mutations: New Insights and Future Perspectives in this Complex Clinical Scenario.

Russo A et al.

International Journal of Molecular Sciences, 2019

Epidermal Growth Factor Receptor (EGFR) Kinase Inhibitors and Non-Small Cell Lung Cancer (NSCLC) - Advances in Molecular Diagnostic Techniques to Facilitate Targeted Therapy.

Ghafoor Q et al.

Pathology Oncology Research : Por, 2018

Idylla assay and next generation sequencing: an integrated EGFR mutational testing algorithm.

De Luca C et al.

Journal of Clinical Pathology, 2018

Expanding the search for significant EGFR mutations in NSCLC outside of the tyrosine kinase domain with next-generation sequencing.

Stein MK et al.

Medical Oncology (northwood, London, England), 2017

Profile of the therascreen® EGFR RGQ PCR kit as a companion diagnostic for gefitinib in non-small cell lung cancer.

Hsiue EH et al.

Expert Review of Molecular Diagnostics, 2016

Not all epidermal growth factor receptor mutations in lung cancer are created equal: Perspectives for individualized treatment strategy.

Kobayashi Y et al.

Cancer Science, 2016

EGFR Exon 18 Mutations in Lung Cancer: Molecular Predictors of Augmented Sensitivity to Afatinib or Neratinib as Compared with First- or Third-Generation TKIs.

Kobayashi Y et al.

Clinical Cancer Research : an Official Journal of the American Association for Cancer Research, 2015

Compound EGFR mutations and response to EGFR tyrosine kinase inhibitors.

Kobayashi S et al.

Journal of Thoracic Oncology : Official Publication of the International Association for the Study of Lung Cancer, 2013

[Molecular profiling of non-small cell lung cancer].

Gibault L et al.

Revue De Pneumologie Clinique, 0

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