Varaico: Literature-Extracted Genetic Variants

Gene:RPA1
Variant:p.I33S
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RPA1

NM_002945.5:p.I33S

Associated Papers

Microhomology-mediated end joining acts directly on replication forks to repair single-ended double strand breaks.

Li S et al.

Biorxiv : the Preprint Server for Biology, 2026

Targeting the non-coding genome and temozolomide signature enables CRISPR-mediated glioma oncolysis.

Tan IL et al.

Cell Reports, 2023

Cancer-specific loss of TERT activation sensitizes glioblastoma to DNA damage.

Amen AM et al.

Proceedings of the National Academy of Sciences of the United States of America, 2021

33758097 (PubMed )
Supplement: pnas.2008772118.sapp.pdf

Increased RPA1 gene dosage affects genomic stability potentially contributing to 17p13.3 duplication syndrome.

Outwin E et al.

Plos Genetics, 2011

Growth inhibition of glioblastoma cells by human Pur(alpha).

Darbinian N et al.

Journal of Cellular Physiology, 2001

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."