Varaico: Literature-Extracted Genetic Variants

Gene:RPA1
Variant:p.Y42F
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RPA1

NM_002945.5:p.Y42F

Associated Papers

Comprehensive mutational analysis of the checkpoint signaling function of Rpa1/Ssb1 in fission yeast.

Xu YJ et al.

Plos Genetics, 2023

Comprehensive mutational analysis of the checkpoint signaling function of Rpa1/Ssb1 in fission yeast.

Xu YJ et al.

Biorxiv : the Preprint Server for Biology, 2023

The Bloom syndrome complex senses RPA-coated single-stranded DNA to restart stalled replication forks.

Shorrocks AK et al.

Nature Communications, 2021

33500419 (PubMed )
Supplement: 41467_2020_20818_MOESM2_ESM.pdf

PRP19 transforms into a sensor of RPA-ssDNA after DNA damage and drives ATR activation via a ubiquitin-mediated circuitry.

Maréchal A et al.

Molecular Cell, 2014

In vitro analysis of the role of replication protein A (RPA) and RPA phosphorylation in ATR-mediated checkpoint signaling.

Lindsey-Boltz LA et al.

The Journal of Biological Chemistry, 2012

Cellular functions of human RPA1. Multiple roles of domains in replication, repair, and checkpoints.

Haring SJ et al.

The Journal of Biological Chemistry, 2008

Mutational analysis of thirty-two double-strand DNA break repair genes in breast and pancreatic cancers.

Wang X et al.

Cancer Research, 2008

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."