Associated Papers
Decoding Cancer Variants of Unknown Significance for Helicase-Nuclease-RPA Complexes Orchestrating DNA Repair During Transcription and Replication.
Tsutakawa SE et al.
Frontiers in Molecular Biosciences, 2021
The presence of extra chromosomes leads to genomic instability.
Passerini V et al.
Nature Communications, 2016
RPA provides checkpoint-independent cell cycle arrest and prevents recombination at uncapped telomeres of Saccharomyces cerevisiae.
Grandin N et al.
Dna Repair, 2013
Functional characterization of a cancer causing mutation in human replication protein A.
Hass CS et al.
Molecular Cancer Research : Mcr, 2010
Mutation in Rpa1 results in defective DNA double-strand break repair, chromosomal instability and cancer in mice.
Wang Y et al.
Nature Genetics, 2005
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