Varaico: Literature-Extracted Genetic Variants

Gene:RPA1
Variant:p.E277A
Back to variants list

RPA1

NM_002945.5:p.E277A

Associated Papers

The canonical RPA complex interacts with Est3 to regulate yeast telomerase activity.

Moeller-McCoy CA et al.

Proceedings of the National Academy of Sciences of the United States of America, 2025

39913192 (PubMed )
Supplement: pnas.2419309122.sapp.pdf

RADX interacts with single-stranded DNA to promote replication fork stability.

Schubert L et al.

Embo Reports, 2017

FANCJ helicase uniquely senses oxidative base damage in either strand of duplex DNA and is stimulated by replication protein A to unwind the damaged DNA substrate in a strand-specific manner.

Suhasini AN et al.

The Journal of Biological Chemistry, 2009

Cellular functions of human RPA1. Multiple roles of domains in replication, repair, and checkpoints.

Haring SJ et al.

The Journal of Biological Chemistry, 2008

Replication protein A interactions with DNA: differential binding of the core domains and analysis of the DNA interaction surface.

Wyka IM et al.

Biochemistry, 2003

Select a paper to view details
UCSC Genome Browser·Imprint·Privacy·Terms·Feedback·Email Updates·

Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."