Associated Papers
Microhomology-mediated end joining acts directly on replication forks to repair single-ended double strand breaks.
Li S et al.
Biorxiv : the Preprint Server for Biology, 2026
Valproic Acid Regulates HR and Cell Cycle Through MUS81-pRPA2 Pathway in Response to Hydroxyurea.
Su B et al.
Frontiers in Oncology, 2021
Maternal BCAS2 protects genomic integrity in mouse early embryonic development.
Xu Q et al.
Development (cambridge, England), 2015
Phosphorylation and cellular function of the human Rpa2 N-terminus in the budding yeast Saccharomyces cerevisiae.
Ghospurkar PL et al.
Experimental Cell Research, 2015
Phosphorylated RPA recruits PALB2 to stalled DNA replication forks to facilitate fork recovery.
Murphy AK et al.
The Journal of Cell Biology, 2014
The role of RPA2 phosphorylation in homologous recombination in response to replication arrest.
Shi W et al.
Carcinogenesis, 2010
Human RPA phosphorylation by ATR stimulates DNA synthesis and prevents ssDNA accumulation during DNA-replication stress.
Vassin VM et al.
Journal of Cell Science, 2009
Sequential and synergistic modification of human RPA stimulates chromosomal DNA repair.
Anantha RW et al.
The Journal of Biological Chemistry, 2007
The ATR-mediated S phase checkpoint prevents rereplication in mammalian cells when licensing control is disrupted.
Liu E et al.
The Journal of Cell Biology, 2007
The Mre11-Rad50-Nbs1 complex acts both upstream and downstream of ataxia telangiectasia mutated and Rad3-related protein (ATR) to regulate the S-phase checkpoint following UV treatment.
Olson E et al.
The Journal of Biological Chemistry, 2007
RPA2 is a direct downstream target for ATR to regulate the S-phase checkpoint.
Olson E et al.
The Journal of Biological Chemistry, 2006
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