Associated Papers
MePCE promotes homologous recombination through coordinating R-loop resolution at DNA double-stranded breaks.
Devanathan SK et al.
Cell Reports, 2025
SIRT1 regulates DNA damage signaling through the PP4 phosphatase complex.
Rasti G et al.
Nucleic Acids Research, 2023
The epigenetic regulator LSH maintains fork protection and genomic stability via MacroH2A deposition and RAD51 filament formation.
Xu X et al.
Nature Communications, 2021
A cohesin/HUSH- and LINC-dependent pathway controls ribosomal DNA double-strand break repair.
Marnef A et al.
Genes & Development, 2019
Human RPA phosphorylation by ATR stimulates DNA synthesis and prevents ssDNA accumulation during DNA-replication stress.
Vassin VM et al.
Journal of Cell Science, 2009
RPA2 is a direct downstream target for ATR to regulate the S-phase checkpoint.
Olson E et al.
The Journal of Biological Chemistry, 2006
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