Associated Papers
Is subretinal AAV gene replacement still the only viable treatment option for choroideremia?
Han RC et al.
Expert Opinion on Orphan Drugs, 2021
In silico Mapping of Protein Unfolding Mutations for Inherited Disease.
McCafferty CL et al.
Scientific Reports, 2016
27905547 (PubMed )
Supplement: srep37298-s1.pdf
Aromatic residues in the substrate cleft of RPE65 protein govern retinol isomerization and modulate its progression.
Chander P et al.
The Journal of Biological Chemistry, 2012
Identification of the key residues determining the product specificity of isomerohydrolase.
Takahashi Y et al.
Biochemistry, 2012
RPE65, visual cycle retinol isomerase, is not inherently 11-cis-specific: support for a carbocation mechanism of retinol isomerization.
Redmond TM et al.
The Journal of Biological Chemistry, 2010
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