Varaico: Literature-Extracted Genetic Variants

Gene:RPGR
Variant:p.G12V
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RPGR

NM_001034853.2:p.G12V

Associated Papers

Galectin-8 binds to the Farnesylated C-terminus of K-Ras4B and Modifies Ras/ERK Signaling and Migration in Pancreatic and Lung Carcinoma Cells.

Meinohl C et al.

Cancers, 2019

31861875 (PubMed )
Supplement: cancers-12-00030-s001.zip › cancers-672634-Suppl-final › cancers-672634-suppl-final.docx

High-resolution melting analysis as a sensitive prescreening diagnostic tool to detect KRAS , BRAF , PIK3CA , and AKT1 mutations in formalin-fixed, paraffin-embedded tissues.

Ney JT et al.

Archives of Pathology & Laboratory Medicine, 2012

Allosteric modulation of Ras-GTP is linked to signal transduction through RAF kinase.

Buhrman G et al.

The Journal of Biological Chemistry, 2011

Conformational states of human rat sarcoma (Ras) protein complexed with its natural ligand GTP and their role for effector interaction and GTP hydrolysis.

Spoerner M et al.

The Journal of Biological Chemistry, 2010

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."