Associated Papers
NKX2-1 regulates cell survival, maturation, and DNA-damage responses as a cofactor of RUNX1 in T-cell acute lymphoblastic leukemia.
Van Aerschot L et al.
Haematologica, 2026
Ribosomal protein L5 (RPL5/uL18) I60V mutation is associated to increased translation and modulates drug sensitivity in T-cell acute lymphoblastic leukemia cells.
Bacci L et al.
Biochemical Pharmacology, 2026
Clinical features, mutational landscape and their prognostic impact in Chinese paediatric patients with T-cell lymphoblastic lymphoma.
Li Y et al.
British Journal of Haematology, 2025
Leveraging genomic diagnostics for prognostics and therapeutics in pediatric acute leukemia.
Newman H et al.
Hemasphere, 2025
Genomics of T-lymphoblastic leukemia/lymphoma: 2023 SH/EAHP workshop proceedings.
Kanagal-Shamanna R et al.
American Journal of Clinical Pathology, 2025
Ribosome specialization by cancer-associated ribosomal protein mutations: progress made and open questions.
Caruso M et al.
Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences, 2025
Decoding ribosome complexity: role of ribosomal proteins in cancer and disease.
Fuentes P et al.
Nar Cancer, 2024
Rare Drivers at Low Prevalence with High Cancer Effects in T-Cell and B-Cell Pediatric Acute Lymphoblastic Leukemia.
Mandell JD et al.
International Journal of Molecular Sciences, 2024
Integrated mutational landscape analysis of poorly differentiated high-grade neuroendocrine carcinoma of the uterine cervix.
Bellone S et al.
Proceedings of the National Academy of Sciences of the United States of America, 2024
Ribosomal protein mutations and cell competition: autonomous and nonautonomous effects on a stress response.
Kiparaki M et al.
Genetics, 2023
Transcription factor NKX2-1 drives serine and glycine synthesis addiction in cancer.
Heylen E et al.
British Journal of Cancer, 2023
Principles of human pre-60 S biogenesis.
Broeck AV et al.
Biorxiv : the Preprint Server for Biology, 2023
FUS regulates a subset of snoRNA expression and modulates the level of rRNA modifications.
Gawade K et al.
Scientific Reports, 2023
Translation defects in ribosomopathies.
Boussaid I et al.
Current Opinion in Hematology, 2022
Transcriptome-wide subtyping of pediatric and adult T cell acute lymphoblastic leukemia in an international study of 707 cases.
Dai YT et al.
Proceedings of the National Academy of Sciences of the United States of America, 2022
Cell autonomous and non-autonomous consequences of deviations in translation machinery on organism growth and the connecting signalling pathways.
Surya A et al.
Open Biology, 2022
Exploitation of the ribosomal protein L10 R98S mutation to enhance recombinant protein production in mammalian cells.
Verbelen B et al.
Engineering in Life Sciences, 2022
Mutational analysis of ribosomal proteins in a cohort of pediatric patients with T-cell acute lymphoblastic leukemia reveals Q123R, a novel mutation in RPL10.
Bacci L et al.
Frontiers in Genetics, 2022
Ribosomal proteins and human diseases: molecular mechanisms and targeted therapy.
Kang J et al.
Signal Transduction and Targeted Therapy, 2021
Neuronal Nsun2 deficiency produces tRNA epitranscriptomic alterations and proteomic shifts impacting synaptic signaling and behavior.
Blaze J et al.
Nature Communications, 2021
PSEN1-selective gamma-secretase inhibition in combination with kinase or XPO-1 inhibitors effectively targets T cell acute lymphoblastic leukemia.
Govaerts I et al.
Journal of Hematology & Oncology, 2021
Deregulation of the Interleukin-7 Signaling Pathway in Lymphoid Malignancies.
Lodewijckx I et al.
Pharmaceuticals (basel, Switzerland), 2021
Single-cell DNA amplicon sequencing reveals clonal heterogeneity and evolution in T-cell acute lymphoblastic leukemia.
Albertí-Servera L et al.
Blood, 2021
Loss of m1acp3Ψ Ribosomal RNA Modification Is a Major Feature of Cancer.
Babaian A et al.
Cell Reports, 2020
Post-transcriptional regulation of BRG1 by FIRΔexon2 in gastric cancer.
Ailiken G et al.
Oncogenesis, 2020
Translatome analysis reveals altered serine and glycine metabolism in T-cell acute lymphoblastic leukemia cells.
Kampen KR et al.
Nature Communications, 2019
Mechanism of completion of peptidyltransferase centre assembly in eukaryotes.
Kargas V et al.
Elife, 2019
Tightly-orchestrated rearrangements govern catalytic center assembly of the ribosome.
Zhou Y et al.
Nature Communications, 2019
The ribosomal RPL10 R98S mutation drives IRES-dependent BCL-2 translation in T-ALL.
Kampen KR et al.
Leukemia, 2019
Ribosomal Lesions Promote Oncogenic Mutagenesis.
Sulima SO et al.
Cancer Research, 2019
Altered patterns of global protein synthesis and translational fidelity in RPS15-mutated chronic lymphocytic leukemia.
Bretones G et al.
Blood, 2018