Varaico: Literature-Extracted Genetic Variants

Gene:RPS27A
Variant:p.V26L
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RPS27A

NM_002954.6:p.V26L

Associated Papers

The N-terminal region of DNMT3A engages the nucleosome surface to aid chromatin recruitment.

Wapenaar H et al.

Embo Reports, 2024

39528729 (PubMed )
Supplement: 44319_2024_306_MOESM11_ESM.pdf

Determinants of chemoselectivity in ubiquitination by the J2 family of ubiquitin-conjugating enzymes.

Swarnkar A et al.

The Embo Journal, 2024

Cocrystallization of ubiquitin-deubiquitinase complexes through disulfide linkage.

Negron Teron KI et al.

Acta Crystallographica. Section D, Structural Biology, 2023

Crucial roles of the BRCA1-BARD1 E3 ubiquitin ligase activity in homology-directed DNA repair.

Wang M et al.

Molecular Cell, 2023

Using AlphaFold to predict the impact of single mutations on protein stability and function.

Pak MA et al.

Plos One, 2023

36928239 (PubMed )
Supplement: pone.0282689.s001.xlsx › Table_S1

BARD1 reads H2A lysine 15 ubiquitination to direct homologous recombination.

Becker JR et al.

Nature, 2021

Structural insight into BRCA1-BARD1 complex recruitment to damaged chromatin.

Dai L et al.

Molecular Cell, 2021

Structures of monomeric and dimeric PRC2:EZH1 reveal flexible modules involved in chromatin compaction.

Grau D et al.

Nature Communications, 2021

Structural basis for the multi-activity factor Rad5 in replication stress tolerance.

Shen M et al.

Nature Communications, 2021

33436623 (PubMed )
Supplement: 41467_2020_20538_MOESM1_ESM.pdf

PALB2 chromatin recruitment restores homologous recombination in BRCA1-deficient cells depleted of 53BP1.

Belotserkovskaya R et al.

Nature Communications, 2020

Structural Basis of H2B Ubiquitination-Dependent H3K4 Methylation by COMPASS.

Hsu PL et al.

Molecular Cell, 2019

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."