Varaico: Literature-Extracted Genetic Variants

Gene:RPS27A
Variant:p.K29R
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RPS27A

NM_002954.6:p.K29R

Associated Papers

Cullin-associated and neddylation-dissociated protein 1 (CAND1) promotes cardiomyocyte proliferation and heart regeneration by enhancing the ubiquitinated degradation of Mps one binder kinase activator 1b (Mob1b).

Li X et al.

Cell Death and Differentiation, 2025

SLC25A1 and ACLY maintain cytosolic acetyl-CoA and regulate ferroptosis susceptibility via FSP1 acetylation.

Li W et al.

The Embo Journal, 2025

E3 ubiquitin ligase CHIP facilitates cAMP and cGMP signalling cross-talk by polyubiquitinating PDE9A.

Hao X et al.

The Embo Journal, 2025

Sugar-mediated non-canonical ubiquitination impairs Nrf1/NFE2L1 activation.

Yoshida Y et al.

Molecular Cell, 2024

Hyperubiquitylation of DNA helicase RECQL4 by E3 ligase MITOL prevents mitochondrial entry and potentiates mitophagy.

Hussain M et al.

The Journal of Biological Chemistry, 2023

37495109 (PubMed )
Supplement: mmc1.pdf

Orphan quality control shapes network dynamics and gene expression.

Mark KG et al.

Cell, 2023

K27-linked ubiquitylation promotes p97 substrate processing and is essential for cell proliferation.

Shearer RF et al.

The Embo Journal, 2022

SPT16 ubiquitylation by DCAF14-CRL4 regulates FACT binding to histones.

Nakagawa T et al.

Cell Reports, 2022

MITOL-dependent ubiquitylation negatively regulates the entry of PolγA into mitochondria.

Hussain M et al.

Plos Biology, 2021

33657094 (PubMed )
Supplement: pbio.3001139.s010.pdf

Hepatitis B Core Protein Is Post-Translationally Modified through K29-Linked Ubiquitination.

Langerová H et al.

Cells, 2020

Ubiquitination of DNA Damage-Stalled RNAPII Promotes Transcription-Coupled Repair.

Nakazawa Y et al.

Cell, 2020

BLM Potentiates c-Jun Degradation and Alters Its Function as an Oncogenic Transcription Factor.

Priyadarshini R et al.

Cell Reports, 2018

Defects in DNA ligase I trigger PCNA ubiquitylation at Lys 107.

Das-Bradoo S et al.

Nature Cell Biology, 2010

Disease-associated mutant ubiquitin causes proteasomal impairment and enhances the toxicity of protein aggregates.

Tank EM et al.

Plos Genetics, 2009

A role for ubiquitination in mitochondrial inheritance in Saccharomyces cerevisiae.

Fisk HA et al.

The Journal of Cell Biology, 1999

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."