Varaico: Literature-Extracted Genetic Variants

Gene:RPTOR
Variant:p.S722A
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RPTOR

NM_020761.3:p.S722A

Associated Papers

Fine-tuning AMPK in physiology and disease using point-mutant mouse models.

Ashraf N et al.

Disease Models & Mechanisms, 2024

Metabolic stress controls mTORC1 lysosomal localization and dimerization by regulating the TTT-RUVBL1/2 complex.

Kim SG et al.

Molecular Cell, 2013

The association of AMPK with ULK1 regulates autophagy.

Lee JW et al.

Plos One, 2010

Oncogenic MAPK signaling stimulates mTORC1 activity by promoting RSK-mediated raptor phosphorylation.

Carrière A et al.

Current Biology : Cb, 2008

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."