Varaico: Literature-Extracted Genetic Variants

Gene:RRAGB
Variant:p.D163N
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RRAGB

NM_006064.5:p.D163N

Associated Papers

Sestrins function as guanine nucleotide dissociation inhibitors for Rag GTPases to control mTORC1 signaling.

Peng M et al.

Cell, 2014

The folliculin tumor suppressor is a GAP for the RagC/D GTPases that signal amino acid levels to mTORC1.

Tsun ZY et al.

Molecular Cell, 2013

Ragulator is a GEF for the rag GTPases that signal amino acid levels to mTORC1.

Bar-Peled L et al.

Cell, 2012

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."