Varaico: Literature-Extracted Genetic Variants

Gene:RRAGC
Variant:p.W115R
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RRAGC

NM_022157.4:p.W115R

Associated Papers

Multi-omics profiling of longitudinal samples reveals early genomic changes in follicular lymphoma.

Bai B et al.

Blood Cancer Journal, 2024

39191762 (PubMed )
Supplement: 41408_2024_1124_MOESM2_ESM.xlsx › Table_S3

Identification of genetic subtypes in follicular lymphoma.

Shelton V et al.

Blood Cancer Journal, 2024

39112453 (PubMed )
Supplement: 41408_2024_1111_MOESM2_ESM.xlsx › ST5_-_mutations

De novo missense variants in RRAGC lead to a fatal mTORopathy of early childhood.

Reijnders MRF et al.

Genetics in Medicine : Official Journal of the American College of Medical Genetics, 2023

A Rag GTPase dimer code defines the regulation of mTORC1 by amino acids.

Gollwitzer P et al.

Nature Cell Biology, 2022

A nutrient-induced affinity switch controls mTORC1 activation by its Rag GTPase-Ragulator lysosomal scaffold.

Lawrence RE et al.

Nature Cell Biology, 2018

Recurrent Mutations in the MTOR Regulator RRAGC in Follicular Lymphoma.

Ying ZX et al.

Clinical Cancer Research : an Official Journal of the American Association for Cancer Research, 2016

Recurrent mTORC1-activating RRAGC mutations in follicular lymphoma.

Okosun J et al.

Nature Genetics, 2016

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."