Associated Papers
Identifying Multiomic Signatures of X-Linked Retinoschisis-Derived Retinal Organoids and Mice Harboring Patient-Specific Mutation Using Spatiotemporal Single-Cell Transcriptomics.
Chien Y et al.
Advanced Science (weinheim, Baden-wurttemberg, Germany), 2025
Retinoschisin Is Required for Pineal Gland Calcification and Cellular Communication in Pinealocytes of Rats and Mice.
Liu X et al.
Laboratory Investigation; a Journal of Technical Methods and Pathology, 2024
Mouse models of X-linked juvenile retinoschisis have an early onset phenotype, the severity of which varies with genotype.
Liu Y et al.
Human Molecular Genetics, 2019
Boosting activity of high-fidelity CRISPR/Cas9 variants using a tRNAGln-processing system in human cells.
He X et al.
The Journal of Biological Chemistry, 2019
Recapitulating X-Linked Juvenile Retinoschisis in Mouse Model by Knock-In Patient-Specific Novel Mutation.
Chen D et al.
Frontiers in Molecular Neuroscience, 2017
Engineered FnCas12a with enhanced activity through directional evolution in human cells.
Liu X et al.
The Journal of Biological Chemistry, 0
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