Varaico: Literature-Extracted Genetic Variants

Gene:RUNX1
Variant:p.N109D
Back to variants list

RUNX1

NM_001754.5:p.N109D

Associated Papers

Interface-guided phenotyping of coding variants in the transcription factor RUNX1.

Ozturk K et al.

Cell Reports, 2024

38968069 (PubMed )
Supplement: NIHMS2011877-supplement-8.xlsx › Sheet1

RUNX1 Upregulation by Cytotoxic Drugs Promotes Apoptosis.

Speidel D et al.

Cancer Research, 2017

RUNX1 DNA-binding mutants, associated with minimally differentiated acute myelogenous leukemia, disrupt myeloid differentiation.

Cammenga J et al.

Cancer Research, 2007

Functional mutagenesis of AML1/RUNX1 and PEBP2 beta/CBF beta define distinct, non-overlapping sites for DNA recognition and heterodimerization by the Runt domain.

Nagata T et al.

Journal of Molecular Biology, 2001

The leukemia-associated AML1 (Runx1)--CBF beta complex functions as a DNA-induced molecular clamp.

Bravo J et al.

Nature Structural Biology, 2001

Structural analyses of DNA recognition by the AML1/Runx-1 Runt domain and its allosteric control by CBFbeta.

Tahirov TH et al.

Cell, 2001

Select a paper to view details
UCSC Genome Browser·Imprint·Privacy·Terms·Feedback·Email Updates·

Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."