Varaico: Literature-Extracted Genetic Variants

Gene:RUNX1T1
Variant:p.T161A
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RUNX1T1

NM_175634.3:p.T161A

Associated Papers

Heterodimerization of AML1/ETO with CBFβ is required for leukemogenesis but not for myeloproliferation.

Thiel VN et al.

Leukemia, 2017

Runx1 Orchestrates Sphingolipid Metabolism and Glucocorticoid Resistance in Lymphomagenesis.

Kilbey A et al.

Journal of Cellular Biochemistry, 2017

A role for RUNX1 in hematopoiesis and myeloid leukemia.

Ichikawa M et al.

International Journal of Hematology, 2013

Failure of the Ipsogen MutaScreen kit to detect the JAK2 617V>F mutation in samples with additional rare exon 14 mutations: implications for clinical testing and report of a novel 618C>F mutation in addition to 617V>F.

Warshawsky I et al.

Blood, 2010

Definitive hematopoiesis requires Runx1 C-terminal-mediated subnuclear targeting and transactivation.

Dowdy CR et al.

Human Molecular Genetics, 2010

Core binding factor at the crossroads: determining the fate of the HSC.

Link KA et al.

Journal of Cellular Physiology, 2010

RUNX1 and its fusion oncoprotein derivative, RUNX1-ETO, induce senescence-like growth arrest independently of replicative stress.

Wolyniec K et al.

Oncogene, 2009

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."