Associated Papers
RUNX3 inactivates oncogenic MYC through disruption of MYC/MAX complex and subsequent recruitment of GSK3β-FBXW7 cascade.
Oei V et al.
Communications Biology, 2023
A Point Mutation R122C in RUNX3 Promotes the Expansion of Isthmus Stem Cells and Inhibits Their Differentiation in the Stomach.
Douchi D et al.
Cellular and Molecular Gastroenterology and Hepatology, 2022
The Multifaceted Role of TGF-β in Gastrointestinal Tumors.
Sabbadini F et al.
Cancers, 2021
RUNX3 is a novel negative regulator of oncogenic TEAD-YAP complex in gastric cancer.
Qiao Y et al.
Oncogene, 2016
Novel Implications of DNA Damage Response in Drug Resistance of Malignant Cancers Obtained from the Functional Interaction between p53 Family and RUNX2.
Ozaki T et al.
Biomolecules, 2015
RUNX family members are covalently modified and regulated by PIAS1-mediated sumoylation.
Kim JH et al.
Oncogenesis, 2014
Context-dependent activation of Wnt signaling by tumor suppressor RUNX3 in gastric cancer cells.
Ju X et al.
Cancer Science, 2014
RUNX Family Participates in the Regulation of p53-Dependent DNA Damage Response.
Ozaki T et al.
International Journal of Genomics, 2013
Association of caspase-9 and RUNX3 with inflammatory bowel disease.
Guo C et al.
Tissue Antigens, 2011
RUNX3 modulates DNA damage-mediated phosphorylation of tumor suppressor p53 at Ser-15 and acts as a co-activator for p53.
Yamada C et al.
The Journal of Biological Chemistry, 2010
Role of RUNX3 in bone morphogenetic protein signaling in colorectal cancer.
Lee CW et al.
Cancer Research, 2010
Cell proliferation-related genetic polymorphisms and gastric cancer risk: systematic review and meta-analysis.
Gao L et al.
European Journal of Human Genetics : Ejhg, 2009
Molecular pathology of RUNX3 in human carcinogenesis.
Subramaniam MM et al.
Biochimica Et Biophysica Acta, 2009
Genetic variants in the Runt-related transcription factor 3 gene contribute to gastric cancer risk in a Chinese population.
Wu D et al.
Cancer Science, 2009
Genetic variants in RUNX3 and risk of bladder cancer: a haplotype-based analysis.
Zhang Z et al.
Carcinogenesis, 2008
RUNX3 inactivation by point mutations and aberrant DNA methylation in bladder tumors.
Kim WJ et al.
Cancer Research, 2005
Redefining tumour suppressor genes: exceptions to the two-hit hypothesis.
Paige AJ
Cellular and Molecular Life Sciences : Cmls, 2003
Causal relationship between the loss of RUNX3 expression and gastric cancer.
Li QL et al.
Cell, 2002
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