Varaico: Literature-Extracted Genetic Variants

Gene:RXRA
Variant:p.S427Y
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RXRA

NM_002957.6:p.S427Y

Associated Papers

The interplay of mutagenesis and ecDNA shapes urothelial cancer evolution.

Nguyen DD et al.

Nature, 2024

39385020 (PubMed )
Supplement: 41586_2024_7955_MOESM11_ESM.xlsx › Figure_3e

Computational refinement identifies functional destructive single nucleotide polymorphisms associated with human retinoid X receptor gene.

Sarkar S et al.

Journal of Biomolecular Structure & Dynamics, 2023

Comprehensive characterization of protein-protein interactions perturbed by disease mutations.

Cheng F et al.

Nature Genetics, 2021

Plasma ctDNA is a tumor tissue surrogate and enables clinical-genomic stratification of metastatic bladder cancer.

Vandekerkhove G et al.

Nature Communications, 2021

33420073 (PubMed )
Supplement: 41467_2020_20493_MOESM3_ESM.xlsx › Supplementary_Data_4

Deep Genomic Sequencing of Bladder Urothelial Carcinoma in Southern Chinese Patients: A Single-Center Study.

Li DY et al.

Frontiers in Oncology, 2021

34055593 (PubMed )
Supplement: Table_1.xlsx › genomic_alterations_information

Recurrent activating mutations of PPARγ associated with luminal bladder tumors.

Rochel N et al.

Nature Communications, 2019

Genomic Activation of PPARG Reveals a Candidate Therapeutic Axis in Bladder Cancer.

Goldstein JT et al.

Cancer Research, 2017

Bladder-cancer-associated mutations in RXRA activate peroxisome proliferator-activated receptors to drive urothelial proliferation.

Halstead AM et al.

Elife, 2017

Pan-urologic cancer genomic subtypes that transcend tissue of origin.

Chen F et al.

Nature Communications, 2017

28775315 (PubMed )
Supplement: 41467_2017_289_MOESM7_ESM.xlsx › mutation_data

Multiplex PCR and Next Generation Sequencing for the Non-Invasive Detection of Bladder Cancer.

Ward DG et al.

Plos One, 2016

26901314 (PubMed )
Supplement: pone.0149756.s006.xlsx › Sheet1

Comprehensive molecular characterization of urothelial bladder carcinoma.

Unknown Author

Nature, 2014

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