Associated Papers
A structurally informed human protein-protein interactome reveals proteome-wide perturbations caused by disease mutations.
Xiong D et al.
Nature Biotechnology, 2025
Reannotation of cancer mutations based on expressed RNA transcripts reveals functional non-coding mutations in melanoma.
Pepe D et al.
American Journal of Human Genetics, 2025
Diagnostic and prognostic genomic aberrations in upper tract urothelial carcinoma can be identified in focal barbotage samples.
Axelsson TA et al.
Bju International, 2025
The interplay of mutagenesis and ecDNA shapes urothelial cancer evolution.
Nguyen DD et al.
Nature, 2024
Exploring the molecular pathways of the activation process in PPARγ recurrent bladder cancer mutants.
de Oliveira VM et al.
The Journal of Chemical Physics, 2024
Whole-genome mapping of APOBEC mutagenesis in metastatic urothelial carcinoma identifies driver hotspot mutations and a novel mutational signature.
Nakauma-González JA et al.
Cell Genomics, 2024
Computational refinement identifies functional destructive single nucleotide polymorphisms associated with human retinoid X receptor gene.
Sarkar S et al.
Journal of Biomolecular Structure & Dynamics, 2023
Identification of T Cell Receptors Targeting a Neoantigen Derived from Recurrently Mutated FGFR3.
Tate T et al.
Cancers, 2023
RXRA DT448/9PP generates a dominant active variant capable of inducing maturation in acute myeloid leukemia cells.
Di Martino O et al.
Haematologica, 2022
Systematic Pan-Cancer Characterization of Nuclear Receptors Identifies Potential Cancer Biomarkers and Therapeutic Targets.
Jiang J et al.
Cancer Research, 2022
Stage-stratified molecular profiling of non-muscle-invasive bladder cancer enhances biological, clinical, and therapeutic insight.
Hurst CD et al.
Cell Reports. Medicine, 2021
The effect of S427F mutation on RXRα activity depends on its dimeric partner.
Galdadas I et al.
Chemical Science, 2021
p53 mitigates the effects of oncogenic HRAS in urothelial cells via the repression of MCOLN1.
Jung J et al.
Iscience, 2021
Cell-Intrinsic Tumorigenic Functions of PPARγ in Bladder Urothelial Carcinoma.
Sanchez DJ et al.
Molecular Cancer Research : Mcr, 2021
Comprehensive characterization of protein-protein interactions perturbed by disease mutations.
Cheng F et al.
Nature Genetics, 2021
My personal mutanome: a computational genomic medicine platform for searching network perturbing alleles linking genotype to phenotype.
Zhou Y et al.
Genome Biology, 2021
Plasma ctDNA is a tumor tissue surrogate and enables clinical-genomic stratification of metastatic bladder cancer.
Vandekerkhove G et al.
Nature Communications, 2021
Deep Genomic Sequencing of Bladder Urothelial Carcinoma in Southern Chinese Patients: A Single-Center Study.
Li DY et al.
Frontiers in Oncology, 2021
Genomic Instability Signature of Palindromic Non-Coding Somatic Mutations in Bladder Cancer.
Vacher S et al.
Cancers, 2020
Identification of new driver and passenger mutations within APOBEC-induced hotspot mutations in bladder cancer.
Shi MJ et al.
Genome Medicine, 2020
Systematic analysis of the intersection of disease mutations with protein modifications.
Simpson CM et al.
Bmc Medical Genomics, 2019
Analysis of error profiles in deep next-generation sequencing data.
Ma X et al.
Genome Biology, 2019
Recurrent activating mutations of PPARγ associated with luminal bladder tumors.
Rochel N et al.
Nature Communications, 2019
Genomic case report of a low grade bladder tumor metastasis to lung.
Van Every MJ et al.
Bmc Urology, 2018
Mutational patterns in chemotherapy resistant muscle-invasive bladder cancer.
Liu D et al.
Nature Communications, 2017
Genomic Activation of PPARG Reveals a Candidate Therapeutic Axis in Bladder Cancer.
Goldstein JT et al.
Cancer Research, 2017
Bladder-cancer-associated mutations in RXRA activate peroxisome proliferator-activated receptors to drive urothelial proliferation.
Halstead AM et al.
Elife, 2017
Pan-urologic cancer genomic subtypes that transcend tissue of origin.
Chen F et al.
Nature Communications, 2017
Multiplex PCR and Next Generation Sequencing for the Non-Invasive Detection of Bladder Cancer.
Ward DG et al.
Plos One, 2016
Bioinformatics analysis of thousands of TCGA tumors to determine the involvement of epigenetic regulators in human cancer.
Gnad F et al.
Bmc Genomics, 2015
Comprehensive molecular characterization of urothelial bladder carcinoma.
Unknown Author
Nature, 2014