Associated Papers
Crystal structure of the SALL4-pomalidomide-cereblon-DDB1 complex.
Matyskiela ME et al.
Nature Structural & Molecular Biology, 2020
Thalidomide Inhibits Human iPSC Mesendoderm Differentiation by Modulating CRBN-dependent Degradation of SALL4.
Belair DG et al.
Scientific Reports, 2020
SALL4 mediates teratogenicity as a thalidomide-dependent cereblon substrate.
Matyskiela ME et al.
Nature Chemical Biology, 2018
Thalidomide promotes degradation of SALL4, a transcription factor implicated in Duane Radial Ray syndrome.
Donovan KA et al.
Elife, 2018
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