Varaico: Literature-Extracted Genetic Variants

Gene:SAMD9L
Variant:p.F886fs
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SAMD9L

NM_152703.5:p.F886fs

Associated Papers

SAMD9L acts as an antiviral factor against HIV-1 and primate lentiviruses by restricting viral and cellular translation.

Legrand A et al.

Plos Biology, 2024

Viral host range factors antagonize pathogenic SAMD9 and SAMD9L variants.

Gahr S et al.

Experimental Cell Research, 2023

New SAMD9L heterozygous mutation leading to myelodysplastic syndrome and acute myeloid leukemia: A case report and review of the literature.

Monagel DA

Cancer Reports (hoboken, N.j.), 2023

Structure and function of an effector domain in antiviral factors and tumor suppressors SAMD9 and SAMD9L.

Peng S et al.

Proceedings of the National Academy of Sciences of the United States of America, 2022

SAMD9L autoinflammatory or ataxia pancytopenia disease mutations activate cell-autonomous translational repression.

Russell AJ et al.

Proceedings of the National Academy of Sciences of the United States of America, 2021

Germline SAMD9L truncation variants trigger global translational repression.

Allenspach EJ et al.

The Journal of Experimental Medicine, 2021

Distinct interferon signatures and cytokine patterns define additional systemic autoinflammatory diseases.

de Jesus AA et al.

The Journal of Clinical Investigation, 2020

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."