Varaico: Literature-Extracted Genetic Variants

Gene:SAMHD1
Variant:p.K595R
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SAMHD1

NM_015474.4:p.K595R

Associated Papers

SUMOylation of SAMHD1 at Lysine 595 is required for HIV-1 restriction in non-cycling cells.

Martinat C et al.

Nature Communications, 2021

34321470 (PubMed )
Supplement: 41467_2021_24802_MOESM1_ESM.pdf

PIAS1 potentiates the anti-EBV activity of SAMHD1 through SUMOylation.

Saiada F et al.

Cell & Bioscience, 2021

TRIM21-mediated proteasomal degradation of SAMHD1 regulates its antiviral activity.

Li Z et al.

Embo Reports, 2020

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