Varaico: Literature-Extracted Genetic Variants

Gene:SAMHD1
Variant:p.K494R
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SAMHD1

NM_015474.4:p.K494R

Associated Papers

Acetylation of SAMHD1 at lysine 580 is crucial for blocking HIV-1 infection.

Bulnes-Ramos A et al.

Mbio, 2024

De-ubiquitination of SAMHD1 by USP7 promotes DNA damage repair to overcome oncogenic stress and affect chemotherapy sensitivity.

Liu J et al.

Oncogene, 2023

SAMHD1 deacetylation by SIRT1 promotes DNA end resection by facilitating DNA binding at double-strand breaks.

Kapoor-Vazirani P et al.

Nature Communications, 2022

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."