Associated Papers
De-ubiquitination of SAMHD1 by USP7 promotes DNA damage repair to overcome oncogenic stress and affect chemotherapy sensitivity.
Liu J et al.
Oncogene, 2023
SAMHD1 deacetylation by SIRT1 promotes DNA end resection by facilitating DNA binding at double-strand breaks.
Kapoor-Vazirani P et al.
Nature Communications, 2022
SAMHD1 in cancer: curse or cure?
Schott K et al.
Journal of Molecular Medicine (berlin, Germany), 2022
Dual roles of SAMHD1 in tumor development and chemoresistance to anticancer drugs.
Chen Z et al.
Oncology Letters, 2021
SAMHD1 Promotes DNA End Resection to Facilitate DNA Repair by Homologous Recombination.
Daddacha W et al.
Cell Reports, 2017
Single-Stranded Nucleic Acids Bind to the Tetramer Interface of SAMHD1 and Prevent Formation of the Catalytic Homotetramer.
Seamon KJ et al.
Biochemistry, 2016
Restriction of virus infection but not catalytic dNTPase activity is regulated by phosphorylation of SAMHD1.
Welbourn S et al.
Journal of Virology, 2013
Identification and characterization of naturally occurring splice variants of SAMHD1.
Welbourn S et al.
Retrovirology, 2012
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