Associated Papers
SAMHD1 in cancer: curse or cure?
Schott K et al.
Journal of Molecular Medicine (berlin, Germany), 2022
Defective modulation of LINE-1 retrotransposition by cancer-associated SAMHD1 mutants.
Gao W et al.
Biochemical and Biophysical Research Communications, 2019
The missing link: allostery and catalysis in the anti-viral protein SAMHD1.
Morris ER et al.
Biochemical Society Transactions, 2019
The SAMHD1-mediated block of LINE-1 retroelements is regulated by phosphorylation.
Herrmann A et al.
Mobile Dna, 2018
A Highly Active Isoform of Lentivirus Restriction Factor SAMHD1 in Mouse.
Bloch N et al.
The Journal of Biological Chemistry, 2017
CyclinA2-Cyclin-dependent Kinase Regulates SAMHD1 Protein Phosphohydrolase Domain.
Yan J et al.
The Journal of Biological Chemistry, 2015
Structural basis of allosteric activation of sterile α motif and histidine-aspartate domain-containing protein 1 (SAMHD1) by nucleoside triphosphates.
Koharudin LM et al.
The Journal of Biological Chemistry, 2014
Mechanism of allosteric activation of SAMHD1 by dGTP.
Ji X et al.
Nature Structural & Molecular Biology, 2013
Tetramerization of SAMHD1 is required for biological activity and inhibition of HIV infection.
Yan J et al.
The Journal of Biological Chemistry, 2013
Structural insight into dGTP-dependent activation of tetrameric SAMHD1 deoxynucleoside triphosphate triphosphohydrolase.
Zhu C et al.
Nature Communications, 2013
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