Varaico: Literature-Extracted Genetic Variants

Gene:SARS1
Variant:p.T429A
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SARS1

NM_006513.4:p.T429A

Associated Papers

Seryl-tRNA synthetase promotes translational readthrough by mRNA binding and involvement of the selenocysteine incorporation machinery.

Liu Z et al.

Nucleic Acids Research, 2023

Mutations of the aminoacyl-tRNA-synthetases SARS and WARS2 are implicated in the etiology of autosomal recessive intellectual disability.

Musante L et al.

Human Mutation, 2017

Competitive binding between Seryl-tRNA synthetase/YY1 complex and NFKB1 at the distal segment results in differential regulation of human vegfa promoter activity during angiogenesis.

Fu CY et al.

Nucleic Acids Research, 2017

Unique domain appended to vertebrate tRNA synthetase is essential for vascular development.

Xu X et al.

Nature Communications, 2012

Noncanonical activity of seryl-tRNA synthetase is involved in vascular development.

Fukui H et al.

Circulation Research, 2009

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."