Varaico: Literature-Extracted Genetic Variants

Gene:SCARB1
Variant:p.T175A
Back to variants list

SCARB1

NM_005505.5:p.T175A

Associated Papers

Zebrafish as outgroup model to study evolution of scavenger receptor class B type I functions.

Verwilligen RAF et al.

Biochimica Et Biophysica Acta. Molecular and Cell Biology of Lipids, 2023

Scavenger receptor class B type I genetic variants associated with disease severity in chronic hepatitis C virus infection.

Arandhara VL et al.

Journal of Medical Virology, 2023

SR-B1's Next Top Model: Structural Perspectives on the Functions of the HDL Receptor.

Powers HR et al.

Current Atherosclerosis Reports, 2022

Genetics and regulation of HDL metabolism.

Kardassis D et al.

Biochimica Et Biophysica Acta. Molecular and Cell Biology of Lipids, 2022

SR-B1, a Key Receptor Involved in the Progression of Cardiovascular Disease: A Perspective from Mice and Human Genetic Studies.

Gracia-Rubio I et al.

Biomedicines, 2021

Impact of protein glycosylation on lipoprotein metabolism and atherosclerosis.

Pirillo A et al.

Cardiovascular Research, 2021

Human variant of scavenger receptor BI (R174C) exhibits impaired cholesterol transport functions.

May SC et al.

Journal of Lipid Research, 2021

Reduced CETP glycosylation and activity in patients with homozygous B4GALT1 mutations.

van den Boogert MAW et al.

Journal of Inherited Metabolic Disease, 2020

Rare P376L variant in the SR-BI gene associates with HDL dysfunction and risk of cardiovascular disease.

Samadi S et al.

Clinical Biochemistry, 2019

Association of Endonuclease G Gene Variants with Cardiovascular Disease Risk Factors.

Etehad Roodi N et al.

Reports of Biochemistry & Molecular Biology, 2019

Proline residues in scavenger receptor-BI's C-terminal region support efficient cholesterol transport.

Proudfoot SC et al.

The Biochemical Journal, 2019

Rare SCARB1 mutations associate with high-density lipoprotein cholesterol but not with coronary artery disease.

Helgadottir A et al.

European Heart Journal, 2018

New insights into the role of glycosylation in lipoprotein metabolism.

van den Boogert MAW et al.

Current Opinion in Lipidology, 2017

Exome chip meta-analysis identifies novel loci and East Asian-specific coding variants that contribute to lipid levels and coronary artery disease.

Lu X et al.

Nature Genetics, 2017

29083407 (PubMed )
Supplement: NIHMS909133-supplement-2.xlsx › Supplementary_Table_11

Scavenger receptor class B member 1 (SCARB1) variants modulate hepatitis C virus replication cycle and viral load.

Westhaus S et al.

Journal of Hepatology, 2017

Single amino acid mutation of SR-BI decreases infectivity of hepatitis C virus derived from cell culture in a cell culture model.

Gao R et al.

World Journal of Gastroenterology, 2017

SR-B1 and PDZK1: partners in HDL regulation.

Trigatti BL

Current Opinion in Lipidology, 2017

Lipoprotein profiles in human heterozygote carriers of a functional mutation P297S in scavenger receptor class B1.

Ljunggren SA et al.

Biochimica Et Biophysica Acta, 2015

Genetic contribution of SCARB1 variants to lipid traits in African Blacks: a candidate gene association study.

Niemsiri V et al.

Bmc Medical Genetics, 2015

A coding variant in SR-BI (I179N) significantly increases atherosclerosis in mice.

Picataggi A et al.

Mammalian Genome : Official Journal of the International Mammalian Genome Society, 2013

Functional genomics of the human high-density lipoprotein receptor scavenger receptor BI: an old dog with new tricks.

Chadwick AC et al.

Current Opinion in Endocrinology, Diabetes, and Obesity, 2013

Genetic studies in mice and humans reveal new physiological roles for the high-density lipoprotein receptor scavenger receptor class B type I.

Hoekstra M et al.

Current Opinion in Lipidology, 2012

Functional characterization of newly-discovered mutations in human SR-BI.

Chadwick AC et al.

Plos One, 2012

Novel mutations in scavenger receptor BI associated with high HDL cholesterol in humans.

Brunham LR et al.

Clinical Genetics, 2011

Select a paper to view details
UCSC Genome Browser·Imprint·Privacy·Terms·Feedback·Email Updates·

Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."