Associated Papers
Pharmacologic Characterization of LTGO-33, a Selective Small Molecule Inhibitor of the Voltage-Gated Sodium Channel NaV1.8 with a Unique Mechanism of Action.
Gilchrist JM et al.
Molecular Pharmacology, 2024
Genetic Profiling of Sodium Channels in Diabetic Painful and Painless and Idiopathic Painful and Painless Neuropathies.
Almomani R et al.
International Journal of Molecular Sciences, 2023
Gene variant effects across sodium channelopathies predict function and guide precision therapy.
Brunklaus A et al.
Brain : a Journal of Neurology, 2022
Familial trigeminal neuralgia - a systematic clinical study with a genomic screen of the neuronal electrogenisome.
Di Stefano G et al.
Cephalalgia : an International Journal of Headache, 2020
Optimizing clinical exome design and parallel gene-testing for recessive genetic conditions in preconception carrier screening: Translational research genomic data from 14,125 exomes.
Capalbo A et al.
Plos Genetics, 2019
Yield of peripheral sodium channels gene screening in pure small fibre neuropathy.
Eijkenboom I et al.
Journal of Neurology, Neurosurgery, and Psychiatry, 2019
Annotation of functional impact of voltage-gated sodium channel mutations.
Hinard V et al.
Human Mutation, 2017
Voltage-gated sodium channels and pain-related disorders.
Kanellopoulos AH et al.
Clinical Science (london, England : 1979), 2016
Painful peripheral neuropathy and sodium channel mutations.
Hoeijmakers JG et al.
Neuroscience Letters, 2015
Exonic mutations in SCN9A (NaV1.7) are found in a minority of patients with erythromelalgia.
Zhang Z et al.
Scandinavian Journal of Pain, 2014
Painful neuropathies: the emerging role of sodium channelopathies.
Brouwer BA et al.
Journal of the Peripheral Nervous System : Jpns, 2014
Small-fiber neuropathy Nav1.8 mutation shifts activation to hyperpolarized potentials and increases excitability of dorsal root ganglion neurons.
Huang J et al.
The Journal of Neuroscience : the Official Journal of the Society for Neuroscience, 2013
Gain-of-function Nav1.8 mutations in painful neuropathy.
Faber CG et al.
Proceedings of the National Academy of Sciences of the United States of America, 2012
Genomic analysis of 21 patients with corneal neuralgia after refractive surgery.
Yuan JH et al.
Pain Reports, 0