Associated Papers
How to differentiate induced pluripotent stem cells into sensory neurons for disease modelling: a functional assessment.
Kalia AK et al.
Stem Cell Research & Therapy, 2024
Pharmacologic Characterization of LTGO-33, a Selective Small Molecule Inhibitor of the Voltage-Gated Sodium Channel NaV1.8 with a Unique Mechanism of Action.
Gilchrist JM et al.
Molecular Pharmacology, 2024
The importance of variant reinterpretation in inherited cardiovascular diseases: Establishing the optimal timeframe.
Fernandez-Falgueras A et al.
Plos One, 2024
38691546 (PubMed )
Supplement: pone.0297914.s001.xlsx › Hoja1
Expanding the genetic causes of small-fiber neuropathy: SCN genes and beyond.
Chan ACY et al.
Muscle & Nerve, 2023
Investigating genotype-phenotype relationship of extreme neuropathic pain disorders in a UK national cohort.
Themistocleous AC et al.
Brain Communications, 2023
Gene variant effects across sodium channelopathies predict function and guide precision therapy.
Brunklaus A et al.
Brain : a Journal of Neurology, 2022
35037686 (PubMed )
Supplement: awac006_Supplementary_Data.pdf
The Human SCN10AG1662S Point Mutation Established in Mice Impacts on Mechanical, Heat, and Cool Sensitivity.
Chidiac C et al.
Frontiers in Pharmacology, 2021
Nav1.7 and other voltage-gated sodium channels as drug targets for pain relief.
Emery EC et al.
Expert Opinion on Therapeutic Targets, 2016
Painful peripheral neuropathy and sodium channel mutations.
Hoeijmakers JG et al.
Neuroscience Letters, 2015
Exonic mutations in SCN9A (NaV1.7) are found in a minority of patients with erythromelalgia.
Zhang Z et al.
Scandinavian Journal of Pain, 2014
Exon 11 skipping of SCN10A coding for voltage-gated sodium channels in dorsal root ganglia.
Schirmeyer J et al.
Channels (austin, Tex.), 2014
Small-fiber neuropathy Nav1.8 mutation shifts activation to hyperpolarized potentials and increases excitability of dorsal root ganglion neurons.
Huang J et al.
The Journal of Neuroscience : the Official Journal of the Society for Neuroscience, 2013
Gain-of-function Nav1.8 mutations in painful neuropathy.
Faber CG et al.
Proceedings of the National Academy of Sciences of the United States of America, 2012
Select a paper to view details