Varaico: Literature-Extracted Genetic Variants

Gene:SCN5A
Variant:p.N927K
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SCN5A

NM_000335.5:p.N927K

Associated Papers

A-type FHFs mediate resurgent currents through TTX-resistant voltage-gated sodium channels.

Xiao Y et al.

Elife, 2022

Predicting changes to INa from missense mutations in human SCN5A.

Clerx M et al.

Scientific Reports, 2018

30143662 (PubMed )
Supplement: 41598_2018_30577_MOESM1_ESM.pdf

Relative resistance to slow inactivation of human cardiac Na+ channel hNav1.5 is reversed by lysine or glutamine substitution at V930 in D2-S6.

Chancey JH et al.

American Journal of Physiology. Cell Physiology, 2007

Prenylamine block of Nav1.5 channel is mediated via a receptor distinct from that of local anesthetics.

Mujtaba MG et al.

Molecular Pharmacology, 2002

Irreversible block of cardiac mutant Na+ channels by batrachotoxin.

Wang SY et al.

Channels (austin, Tex.), 0

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."