Associated Papers
Genetic and Clinical Insights into Inherited Erythromelalgia: A Comprehensive Review of Cases from China and Worldwide.
Li Y et al.
The Journal of Investigative Dermatology, 2026
Mepyramine targets mutant Nav1.7 channels to relieve pain and erythema in primary erythromelalgia patients.
Ducrocq M et al.
Frontiers in Medicine, 2025
Investigating genotype-phenotype relationship of extreme neuropathic pain disorders in a UK national cohort.
Themistocleous AC et al.
Brain Communications, 2023
Unwinding and spiral sliding of S4 and domain rotation of VSD during the electromechanical coupling in Nav1.7.
Huang G et al.
Proceedings of the National Academy of Sciences of the United States of America, 2022
Assessing the impact of pain-linked Nav1.7 variants: An example of two variants with no biophysical effect.
Le Cann K et al.
Channels (austin, Tex.), 2021
Rare NaV1.7 variants associated with painful diabetic peripheral neuropathy.
Blesneac I et al.
Pain, 2018
Q10R mutation in SCN9A gene is associated with generalized epilepsy with febrile seizures plus.
Cen Z et al.
Seizure, 2017
Network topology of NaV1.7 mutations in sodium channel-related painful disorders.
Kapetis D et al.
Bmc Systems Biology, 2017
Mexiletine as a treatment for primary erythromelalgia: normalization of biophysical properties of mutant L858F NaV 1.7 sodium channels.
Cregg R et al.
British Journal of Pharmacology, 2014
Inherited pain: sodium channel Nav1.7 A1632T mutation causes erythromelalgia due to a shift of fast inactivation.
Eberhardt M et al.
The Journal of Biological Chemistry, 2014
A novel SCN9A mutation responsible for primary erythromelalgia and is resistant to the treatment of sodium channel blockers.
Wu MT et al.
Plos One, 2013
Severe case and literature review of primary erythromelalgia: novel SCN9A gene mutation.
Skeik N et al.
Vascular Medicine (london, England), 2012
[Analysis of the families and the clinical phenotypes of the generalized epilepsy associated with adjunct febrile seizure].
Chen X et al.
Zhonghua Er Ke Za Zhi = Chinese Journal of Pediatrics, 2008
Characterization of a familial case with primary erythromelalgia from Taiwan.
Lee MJ et al.
Journal of Neurology, 2007
Mutations in SCN9A, encoding a sodium channel alpha subunit, in patients with primary erythermalgia.
Yang Y et al.
Journal of Medical Genetics, 2004
Phosphorylation of a chronic pain mutation in the voltage-gated sodium channel Nav1.7 increases voltage sensitivity.
Kerth CM et al.
The Journal of Biological Chemistry, 0