Varaico: Literature-Extracted Genetic Variants

Gene:SCN9A
Variant:p.E406K
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SCN9A

NM_001365536.1:p.E406K

Associated Papers

Phosphorylation-driven conformational switching of the ArnA-ArnB complex involved in archaeal motility regulation.

Watad M et al.

Frontiers in Microbiology, 2025

41623621 (PubMed )
Supplement: Table_4.XLSX › PDB100_Data_base

Structural basis for NaV1.7 inhibition by pore blockers.

Zhang J et al.

Nature Structural & Molecular Biology, 2022

Unwinding and spiral sliding of S4 and domain rotation of VSD during the electromechanical coupling in Nav1.7.

Huang G et al.

Proceedings of the National Academy of Sciences of the United States of America, 2022

High-resolution structures of human Nav1.7 reveal gating modulation through α-π helical transition of S6IV.

Huang G et al.

Cell Reports, 2022

Selective Targeting of Nav1.7 with Engineered Spider Venom-Based Peptides.

Neff RA et al.

Channels (austin, Tex.), 2021

Structures of human Nav1.7 channel in complex with auxiliary subunits and animal toxins.

Shen H et al.

Science (new York, N.y.), 2019

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."