Varaico: Literature-Extracted Genetic Variants

Gene:SDHA
Variant:p.V425G
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SDHA

NM_004168.4:p.V425G

Associated Papers

Succinate dehydrogenase deficiency-driven succinate accumulation induces drug resistance in acute myeloid leukemia via ubiquitin-cullin regulation.

Chen Y et al.

Nature Communications, 2024

39537588 (PubMed )
Supplement: 41467_2024_53398_MOESM1_ESM.pdf

Succinate dehydrogenase variants in paraganglioma: why are B subunit variants 'bad'?

Gruber LM et al.

Endocrine Oncology (bristol, England), 2023

37434649 (PubMed )
Supplement: supplementary_table_1.xlsx › Missense_Variants

Next-Generation Sequencing-Directed Therapy in Patients with Metastatic Breast Cancer in Routine Clinical Practice.

Bruzas S et al.

Cancers, 2021

34572791 (PubMed )
Supplement: cancers-13-04564-s001.zip › cancers-1336427-supplementary › Supplementary_material › Table_S1_-_Genetic_alterations_identified_by_NGS_in_95_patients_with_metastatic_breast_cancer.xlsx › Table_S1

Androgen receptor (AR) antagonism triggers acute succinate-mediated adaptive responses to reactivate AR signaling.

Saxena N et al.

Embo Molecular Medicine, 2021

33709547 (PubMed )
Supplement: EMMM-13-e13427-s006.pdf

Centromeric cohesion failure invokes a conserved choreography of chromosomal mis-segregations in pancreatic neuroendocrine tumor.

Quevedo R et al.

Genome Medicine, 2020

32345369 (PubMed )
Supplement: 13073_2020_730_MOESM5_ESM.xlsx › SD._Exome_SNVs

Development of Personalized Therapeutic Strategies by Targeting Actionable Vulnerabilities in Metastatic and Chemotherapy-Resistant Breast Cancer PDXs.

Punzi S et al.

Cells, 2019

31216647 (PubMed )
Supplement: cells-08-00605-s001.zip › cells-502088-SI › TableS2.xlsx › EXOME-seq_PDXs
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