Varaico: Literature-Extracted Genetic Variants

Gene:SDS
Variant:p.E288K
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SDS

NM_006843.3:p.E288K

Associated Papers

Nick sealing of polβ mismatch insertion products by LIG1 and LIG3α during 8-oxoG bypass leads to mutagenic or error-free base excision repair.

Lee KM et al.

The Journal of Biological Chemistry, 2025

40286853 (PubMed )
Supplement: mmc1.pdf

Defective Nucleotide Release by DNA Polymerase β Mutator Variant E288K Is the Basis of Its Low Fidelity.

Mahmoud MM et al.

Biochemistry, 2017

Nuclear Receptor-Like Structure and Interaction of Congenital Heart Disease-Associated Factors GATA4 and NKX2-5.

Kinnunen S et al.

Plos One, 2015

Catalytic effects of mutations of distant protein residues in human DNA polymerase β: theory and experiment.

Klvaňa M et al.

Biochemistry, 2012

Function of Escherichia coli biotin carboxylase requires catalytic activity of both subunits of the homodimer.

Janiyani K et al.

The Journal of Biological Chemistry, 2001

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."