Varaico: Literature-Extracted Genetic Variants

Gene:SEC61A1
Variant:p.D60G
Back to variants list

SEC61A1

NM_013336.4:p.D60G

Associated Papers

Structural insights into TRAP association with ribosome-Sec61 complex and translocon inhibition by a CADA derivative.

Pauwels E et al.

Science Advances, 2023

36867692 (PubMed )
Supplement: sciadv.adf0797_sm.pdf

Inhibition of the SEC61 translocon by mycolactone induces a protective autophagic response controlled by EIF2S1-dependent translation that does not require ULK1 activity.

Hall BS et al.

Autophagy, 2022

Mycolactone enhances the Ca2+ leak from endoplasmic reticulum by trapping Sec61 translocons in a Ca2+ permeable state.

Bhadra P et al.

The Biochemical Journal, 2021

Select a paper to view details
UCSC Genome Browser·Imprint·Privacy·Terms·Feedback·Email Updates·

Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."