Varaico: Literature-Extracted Genetic Variants

Gene:SEC61A1
Variant:p.Q127K
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SEC61A1

NM_013336.4:p.Q127K

Associated Papers

Structural insights into TRAP association with ribosome-Sec61 complex and translocon inhibition by a CADA derivative.

Pauwels E et al.

Science Advances, 2023

36867692 (PubMed )
Supplement: sciadv.adf0797_sm.pdf

Mycolactone enhances the Ca2+ leak from endoplasmic reticulum by trapping Sec61 translocons in a Ca2+ permeable state.

Bhadra P et al.

The Biochemical Journal, 2021

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