Associated Papers
Functional integrity of the SEL1L-HRD1 complex is critical for endoplasmic reticulum-associated degradation and organismal viability.
Zhang X et al.
Proceedings of the National Academy of Sciences of the United States of America, 2026
Structural basis and pathological implications of the dimeric OS9-SEL1L-HRD1 ERAD Core Complex.
Lin LL et al.
Nature Communications, 2026
Functional integrity of the SEL1L-HRD1 complex is critical for ERAD and organismal viability.
Zhang X et al.
Biorxiv : the Preprint Server for Biology, 2025
PCR-based detection of hereditary mutations in SLC2A9, BTBD17, and NECAP1 among native Korean dog breeds.
Kang M et al.
Journal of Veterinary Science, 2025
Structural basis and pathological implications of the dimeric OS9-SEL1L-HRD1 ERAD Core Complex.
Lin LL et al.
Biorxiv : the Preprint Server for Biology, 2025
E3 ubiquitin ligase SYVN1 as a promising therapeutic target for diverse human diseases.
Zhu L et al.
Pharmacological Research, 2025
Purkinje cell-specific deficiency in SEL1L-hrd1 endoplasmic reticulum-associated degradation causes progressive cerebellar ataxia in mice.
Torres M et al.
Jci Insight, 2024
SEL1L-HRD1 interaction is required to form a functional HRD1 ERAD complex.
Lin LL et al.
Nature Communications, 2024
Hypomorphic variants of SEL1L-HRD1 ER-associated degradation are associated with neurodevelopmental disorders.
Wang HH et al.
The Journal of Clinical Investigation, 2024
Hypomorphic human SEL1L and HRD1 variants uncouple multilayered ER-associated degradation machinery.
Umphred-Wilson K et al.
The Journal of Clinical Investigation, 2024
SEL1L-HRD1 interaction is prerequisite for the formation of a functional HRD1 ERAD complex.
Lin LL et al.
Biorxiv : the Preprint Server for Biology, 2023
Unraveling the roles of endoplasmic reticulum-associated degradation in metabolic disorders.
Luo H et al.
Frontiers in Endocrinology, 2023
Genome-wide association study in mice identifies loci affecting liver-related phenotypes including Sel1l influencing serum bile acids.
Wu W et al.
Hepatology (baltimore, Md.), 2016
Genetic Panel Screening of Nearly 100 Mutations Reveals New Insights into the Breed Distribution of Risk Variants for Canine Hereditary Disorders.
Donner J et al.
Plos One, 2016
SEL1L SNP rs12435998, a predictor of glioblastoma survival and response to radio-chemotherapy.
Mellai M et al.
Oncotarget, 2015
A SEL1L mutation links a canine progressive early-onset cerebellar ataxia to the endoplasmic reticulum-associated protein degradation (ERAD) machinery.
Kyöstilä K et al.
Plos Genetics, 2012
DNA testing in neurologic diseases.
O'Brien DP et al.
Journal of Veterinary Internal Medicine, 0
Phenotypic and genetic aspects of hereditary ataxia in dogs.
Stee K et al.
Journal of Veterinary Internal Medicine, 0