Varaico: Literature-Extracted Genetic Variants

Gene:SEMA7A
Variant:p.N559Y
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SEMA7A

NM_003612.5:p.N559Y

Associated Papers

The SEMA7AN559Y mutation facilitates the development of metabolic dysfunction-associated steatotic liver disease by inducing ROS/NLRP3-mediated hepatic cell pyroptosis.

Zhang X et al.

Metabolism: Clinical and Experimental, 2026

SEMA7AR148W mutation promotes lipid accumulation and NAFLD progression via increased localization on the hepatocyte surface.

Zhao N et al.

Jci Insight, 2022

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."