Associated Papers
Lysine-372-dependent SUMOylation inhibits the enzymatic activity of glutamine synthases.
Ling T et al.
Faseb Journal : Official Publication of the Federation of American Societies for Experimental Biology, 2023
The SUMO-specific protease SENP1 deSUMOylates p53 and regulates its activity.
Chauhan KM et al.
Journal of Cellular Biochemistry, 2021
Gain-of-function mutant p53 activates small GTPase Rac1 through SUMOylation to promote tumor progression.
Yue X et al.
Genes & Development, 2017
SUMOylation of synapsin Ia maintains synaptic vesicle availability and is reduced in an autism mutation.
Tang LT et al.
Nature Communications, 2015
Nuclear mobility and activity of FOXA1 with androgen receptor are regulated by SUMOylation.
Sutinen P et al.
Molecular Endocrinology (baltimore, Md.), 2014
Conformational flexibility and changes underlying activation of the SUMO-specific protease SENP1 by remote substrate binding.
Chen CH et al.
Nature Communications, 2014
SUMOylation is required for glycine-induced increases in AMPA receptor surface expression (ChemLTP) in hippocampal neurons.
Jaafari N et al.
Plos One, 2013
Structure-function analysis indicates that sumoylation modulates DNA-binding activity of STAT1.
Grönholm J et al.
Bmc Biochemistry, 2012
Pellino-1, an adaptor protein of interleukin-1 receptor/toll-like receptor signaling, is sumoylated by Ubc9.
Kim JH et al.
Molecules and Cells, 2011
Gain-of-function mutations in TRPM4 cause autosomal dominant isolated cardiac conduction disease.
Liu H et al.
Circulation. Cardiovascular Genetics, 2010
Transcriptional ERRgamma2-mediated activation is regulated by sentrin-specific proteases.
Hentschke M et al.
The Biochemical Journal, 2009
SUMOylation modulates the transcription repressor function of RIP140.
Rytinki MM et al.
The Journal of Biological Chemistry, 2008
Molecular basis of the redox regulation of SUMO proteases: a protective mechanism of intermolecular disulfide linkage against irreversible sulfhydryl oxidation.
Xu Z et al.
Faseb Journal : Official Publication of the Federation of American Societies for Experimental Biology, 2008
Role for KAP1 serine 824 phosphorylation and sumoylation/desumoylation switch in regulating KAP1-mediated transcriptional repression.
Li X et al.
The Journal of Biological Chemistry, 2007
Sumoylation of the transcriptional intermediary factor 1beta (TIF1beta), the Co-repressor of the KRAB Multifinger proteins, is required for its transcriptional activity and is modulated by the KRAB domain.
Mascle XH et al.
The Journal of Biological Chemistry, 2007
Crystal structure of the SENP1 mutant C603S-SUMO complex reveals the hydrolytic mechanism of SUMO-specific protease.
Xu Z et al.
The Biochemical Journal, 2006
Characterization of the localization and proteolytic activity of the SUMO-specific protease, SENP1.
Bailey D et al.
The Journal of Biological Chemistry, 2004
SUMOylation of the ubiquitin ligase IDOL decreases LDL receptor levels and is reversed by SENP1.
Wang JQ et al.
The Journal of Biological Chemistry, 0