Varaico: Literature-Extracted Genetic Variants

Gene:SENP1
Variant:p.V201V
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SENP1

NM_001267594.2:p.V201V

Associated Papers

SUMO4 promotes SUMO deconjugation required for DNA double-strand-break repair.

Garvin AJ et al.

Molecular Cell, 2025

FGFR1 SUMOylation coordinates endothelial angiogenic signaling in angiogenesis.

Zhu X et al.

Proceedings of the National Academy of Sciences of the United States of America, 2022

Atypic SUMOylation of Nor1/NR4A3 regulates neural cell viability and redox sensitivity.

Gagnon J et al.

Faseb Journal : Official Publication of the Federation of American Societies for Experimental Biology, 2021

SUMOylation of the transcription factor ZFHX3 at Lys-2806 requires SAE1, UBC9, and PIAS2 and enhances its stability and function in cell proliferation.

Wu R et al.

The Journal of Biological Chemistry, 2020

Conformational flexibility and changes underlying activation of the SUMO-specific protease SENP1 by remote substrate binding.

Chen CH et al.

Nature Communications, 2014

Desumoylation of homeodomain-interacting protein kinase 2 (HIPK2) through the cytoplasmic-nuclear shuttling of the SUMO-specific protease SENP1.

Kim YH et al.

Febs Letters, 2005

Characterization of the localization and proteolytic activity of the SUMO-specific protease, SENP1.

Bailey D et al.

The Journal of Biological Chemistry, 2004

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."