Varaico: Literature-Extracted Genetic Variants

Gene:SENP3
Variant:p.C532S
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SENP3

NM_015670.6:p.C532S

Associated Papers

GNL3 SUMOylation is essential for DNA double-strand break repair by homologous recombination.

Yang Y et al.

Biorxiv : the Preprint Server for Biology, 2025

PELP1 coordinates the modular assembly and enzymatic activity of the rixosome complex.

Gordon J et al.

Science Advances, 2025

Characterization of nucleolar SUMO isopeptidases unveils a general p53-independent checkpoint of impaired ribosome biogenesis.

Dönig J et al.

Nature Communications, 2023

HMGXB4 Targets Sleeping Beauty Transposition to Germinal Stem Cells.

Devaraj A et al.

International Journal of Molecular Sciences, 2023

Crosstalk between SUMOylation and ubiquitylation controls DNA end resection by maintaining MRE11 homeostasis on chromatin.

Zhang T et al.

Nature Communications, 2022

The AAA ATPase MDN1 Acts as a SUMO-Targeted Regulator in Mammalian Pre-ribosome Remodeling.

Raman N et al.

Molecular Cell, 2016

The SUMO-specific isopeptidase SENP3 regulates MLL1/MLL2 methyltransferase complexes and controls osteogenic differentiation.

Nayak A et al.

Molecular Cell, 2014

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."