Associated Papers
Changes in strand 6B and helix B during neuroserpin inhibition: Implication in severity of clinical phenotype.
Ali MF et al.
Biochimica Et Biophysica Acta. Proteins and Proteomics, 2020
Aggressive natural killer-cell leukemia mutational landscape and drug profiling highlight JAK-STAT signaling as therapeutic target.
Dufva O et al.
Nature Communications, 2018
29674644 (PubMed )
Supplement: 41467_2018_3987_MOESM5_ESM.xlsx › ANKL12
A hydrophobic patch surrounding Trp154 in human neuroserpin controls the helix F dynamics with implications in inhibition and aggregation.
Ali MF et al.
Scientific Reports, 2017
[α1-Antitrypsin deficiency].
Hirai T
Nihon Rinsho. Japanese Journal of Clinical Medicine, 2016
Dynamic local unfolding in the serpin α-1 antitrypsin provides a mechanism for loop insertion and polymerization.
Krishnan B et al.
Nature Structural & Molecular Biology, 2011
Neuroserpin Portland (Ser52Arg) is trapped as an inactive intermediate that rapidly forms polymers: implications for the epilepsy seen in the dementia FENIB.
Belorgey D et al.
European Journal of Biochemistry, 2004
Practical genetics: alpha-1-antitrypsin deficiency and the serpinopathies.
Crowther DC et al.
European Journal of Human Genetics : Ejhg, 2004
Molecular mousetraps, alpha1-antitrypsin deficiency and the serpinopathies.
Lomas DA
Clinical Medicine (london, England), 0
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